Multiflorane triterpene esters from the seeds of Trichosanthes kirilowii
Author(s)
Author(s)
Wu, T.
Cheng, X.-M.
Chou, G.-X.
Wang, Z.-T.
Bashall, A.
Branford-White, C.
Date Issued
2005
Publisher
Wiley
Journal
Helvetica Chimica Acta
Volume
88
Issue
10
Start page
2617
End page
2623
Abstract
Two new multiflorane triterpene esters, (3α,7β)-3,7,29-trihydroxymultiflor-8-ene-3,29-diyl dibenzoate (2) and (3α)-3,29-dihydroxy-7-oxomultiflor-8-ene-3,29-diyl dibenzoate (3) have been isolated from the CHCl3 extract of the seeds of Trichosanthes kirilowii, together with two known compounds, (3α,5α,22E)-24-ethylcholesta-7,22,25(27)-trien-3-ol and darutigenol. The structures of the new compounds were elucidated on the basis of extensive NMR experiments, and by means of an X-ray crystallographic analysis of 2. A preliminary cytotoxicity assay showed that 2 and 3 are basically inactive against the K562 cell line.
SFU Affiliated Publication
No
Availability at SFU Library
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