Wang, Debby DanDebby DanWangMa, L.Zou, B.Yan, H.2021-07-112021-07-112017https://repository.sfu.edu.hk/handle/sfu/846We explore the drug resistance mechanism in non-small cell lung cancer treatment by characterizing the drug-binding site of a protein mutant based on local surface and energy features. These features are transformed to an eigenbinding site space and used for drug resistance level prediction and analysis.enjournal article10.1109/TCBB.2016.2568184