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  4. Development and large-scale validation of the Watch Walk wrist-worn digital gait biomarkers
 
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Development and large-scale validation of the Watch Walk wrist-worn digital gait biomarkers

Author(s)
Choi, Tiffany Ching Man  
Author(s)
Chan, L. L. Y.
Lord, S. R.
Brodie, M. A.
Date Issued
2022
Publisher
Springer
Journal
Scientific Reports
Volume
12
Abstract
Digital gait biomarkers (including walking speed) indicate functional decline and predict hospitalization and mortality. However, waist or lower-limb devices often used are not designed for continuous life-long use. While wrist devices are ubiquitous and many large research repositories include wrist-sensor data, widely accepted and validated digital gait biomarkers derived from wrist-worn accelerometers are not available yet. Here we describe the development of advanced signal processing algorithms that extract digital gait biomarkers from wrist-worn devices and validation using 1-week data from 78,822 UK Biobank participants. Our gait biomarkers demonstrate good test–retest-reliability, strong agreement with electronic walkway measurements of gait speed and self-reported pace and significantly discriminate individuals with poor self-reported health. With the almost universal uptake of smart-watches, our algorithms offer a new approach to remotely monitor life-long population level walking speed, quality, quantity and distribution, evaluate disease progression, predict risk of adverse events and provide digital gait endpoints for clinical trials.
URI
https://repository.sfu.edu.hk/handle/sfu/4419
DOI
10.1038/s41598-022-20327-z
SFU Affiliated Publication
Yes
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